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The life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomics

18 Oct 2014

Abstract excerpt

Viruses have coevolved with their hosts, acquiring strategies to subvert host cellular pathways for effective viral replication and spread. Human cytomegalovirus (HCMV), a widely-spread β-herpesvirus, is a major cause of birth defects and opportunistic infections in HIV-1/AIDS patients. HCMV displays an intricate system-wide modulation of the human cell proteome. An impressive array of virus-host protein...

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PMID: 25327590
DOI: 10.1586/14789450.2014.971116

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