Article

Transcriptome-wide Mendelian randomisation exploring dynamic CD4+ T cell gene expression in colorectal cancer development

2025-04-17

Abstract excerpt

<h4>Background</h4> Recent research has identified a potential protective effect of higher numbers of circulating lymphocytes on colorectal cancer (CRC) development. However, the importance of different lymphocyte subtypes and activation states in CRC development and the biological pathways driving this relationship remain poorly understood and warrant further investigation. Specifically, CD4+ T cells – a highly d...

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Literature Corpus work: 9b869798-5bc0-59eb-8d59-d4fdb8437c3a
DOI: 10.1101/2025.04.15.25325863

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