Article
Integrative multi-omics analysis identifies key genes and colocalized signals associated with colorectal cancer risk.
BMC cancer - 25 Aug 2025
Xia Lianheng, Wang Jiaxin, Gao Jie, Cui Xuan, Song Meiyu, Ding Wukun, Zhang Jiayuan
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) affects approximately 1.9 million people globally each year. While CRC development involves complex genetic and environmental interactions, the underlying molecular mechanisms remain incompletely understood. This study integrated multi-omics data to investigate gene-CRC associations across methylation, expression, and protein levels. METHODS: We obtained summary statistics from...
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