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Article

Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer.

Clinical science (London, England : 1979) - 29 Apr 2022

Hatthakarnkul Phimmada, Quinn Jean A, Ammar Aula, Lynch Gerard, Van Wyk Hester, McMillan Donald C, Thuwajit Chanitra, Edwards Joanne

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer worldwide. Poor survival of CRC associated with the development of tumour metastasis led to the investigation of the potential biomarkers to predict outcomes in CRC patients. Tumour budding (TB) is a well-known independent prognostic marker for poor survival and disease metastasis. Therefore, it has been suggested that TB status is included in routine...

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Identifiers

PMID: 35445707
DOI: 10.1042/CS20210886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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