Article

Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques

2024-02-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> RhCMV/SIV vaccines protect ∼59% of vaccinated rhesus macaques against repeated limiting-dose intra-rectal exposure with highly pathogenic SIVmac239M, but the exact mechanism responsible for the vaccine efficacy is not known. It is becoming evident that complex interactions exist between gut microbiota and the host immune system. Here we aimed to investigate if the rhesus gut...

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Literature Corpus work: a42bb528-3154-5d98-90d9-e73686a823ce
DOI: 10.1101/2024.02.27.582186

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Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaquesDOI 10.1101/2024.02.27.582186Read

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