Back to search

Article

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

2018-11-01

Abstract excerpt

Post-traumatic stress disorder (PTSD) is a common and debilitating disorder. The risk of PTSD following trauma is heritable, but robust common variants have yet to be identified by genome-wide association studies (GWAS). We have collected a multi-ethnic cohort including over 30,000 PTSD cases and 170,000 controls. We first demonstrate significant genetic correlations across 60 PTSD cohorts to evaluate the comparab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9b54235a-f98b-5b9a-a028-c66cb35d5757
DOI
10.1101/458562
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathwaysDOI 10.1101/458562
Select a neighboring publication to make it the new centre.