Article
Genetic association analysis of 300 genes identifies a risk haplotype in SLC18A2 for post-traumatic stress disorder in two independent samples.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2014
Solovieff Nadia, Roberts Andrea L, Ratanatharathorn Andrew, Haloosim Michelle, De Vivo Immaculata, King Anthony P, Liberzon Israel, Aiello Allison, Uddin Monica, Wildman Derek E, Galea Sandro, Smoller Jordan W, Purcell Shaun M, Koenen Karestan C
Abstract excerpt
The genetic architecture of post-traumatic stress disorder (PTSD) remains poorly understood with the vast majority of genetic association studies reporting on single candidate genes. We conducted a large genetic study in trauma-exposed European-American women (N=2538; 845 PTSD cases, 1693 controls) by testing 3742 SNPs across more than 300 genes and conducting polygenic analyses using results from the Psychiatric...
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