Article

Atezolizumab and Granzyme B as Immunotoxin Against PD-L1 Antigen; An Insilico Study

2020-08-13

Abstract excerpt

<h4>Background: </h4> Programmed death-ligand 1 (PD-L1), also called B7 homolog 1 (B7-H1), is a human protein playing an important biomarker role in highly proliferation cells (like cancer cells) which is encoded by the CD274 gene. The interaction between PD-1 and PD-L1 inhibits T cell growth and cytokine secretion. Therefore, PD-L1 negatively regulates immune responses and permits tumor cells to evade immune surv...

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Literature Corpus work: 9b48e6c3-eb07-5de1-8e38-214d8dab2e34
DOI: 10.21203/rs.3.rs-56412/v1

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