Article
ABCF Protein-Mediated Resistance Shapes Bacterial Responses to antibiotics Based on their Type and Concentration
2025-02-13
Abstract excerpt
<h4>ABSTRACT</h4> ABCF ATPases are increasingly recognized as translation factors that rescue stalled ribosomes, whether they encounter challenging mRNA templates or antibiotic-induced stalling. The latter defines ARE ABCF proteins, known for their role in antibiotic resistance. However, in this study, we reveal a broader role of ARE ABCFs in antibiotic-responsive regulation. Using genetic, OMICs, and biochemical...
Topics
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- Antibiotic Resistance in Bacteria
- Bacterial Genetics and Biotechnology
- Drug Transport and Resistance Mechanisms
- Microbial Metabolism and Applications
- Microbial Natural Products and Biosynthesis
- Pneumocystis jirovecii pneumonia detection and treatment
- RNA and protein synthesis mechanisms
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- 745d9f98-c123-5b75-b622-c6a371e69838
- DOI
- 10.1101/2025.02.10.637581
