Article

Microchimerism in the human brain, quantitative assessment and single nuclei profiling establish cell types and diversity

2026-06-10

Abstract excerpt

Bi-directional maternal-fetal exchange during pregnancy creates a long-term microchimerism (Mc) legacy in both individuals, but its presence and cellular fate in human brain are largely unknown. We studied surgically resected epilepsy brain specimens with targetable maternal polymorphisms using polymorphism-specific quantitative PCR. Maternal Mc was prevalent, detectable in 70% of patients, and often at striking q...

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Literature Corpus work: 9ae886ff-f2a5-52fa-b449-9f7d4b0cc9c7
DOI: 10.64898/2026.06.05.730225

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