Article
NFATc acts as a non-canonical phenotypic stability factor for a hybrid epithelial/mesenchymal phenotype
2020-04-18
Abstract excerpt
Metastasis remains the cause of over 90% of cancer-related deaths. Cells undergoing metastasis use phenotypic plasticity to adapt to their changing environmental conditions and avoid therapy and immune response. Reversible transitions between epithelial and mesenchymal phenotypes - Epithelial-Mesenchymal Transition (EMT) and its reverse Mesenchymal-Epithelial Transition (MET) - form a key axis of phenotypic plasti...
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Identifiers and source
- Literature Corpus work
- 9a699f55-d7b2-52e9-a8bd-5b2e2bfba378
- DOI
- 10.1101/2020.04.18.047803
