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Deoxyshikonin Ameliorates High Glucose-Induced Dysfunction of Human Umbilical Vein Endothelial Cells and Promotes Wound Healing in Diabetic Mice by Regulating hsa-HLA- DRB1

2026-06-22

Abstract excerpt

<title>Abstract</title> <p>Background To investigate the molecular mechanism by which deoxyshikonin (DS) modulates hsa-HLA-DRB1 to ameliorate high glucose (HG)-induced dysfunction in human umbilical vein endothelial cells (HUVECs) and to evaluate its regulatory effect on wound healing in a diabetic mouse model, thereby providing an experimental basis and a targeted therapeutic strategy for diabetic foot ulcers (...

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Literature Corpus work: 9a5eba0d-1db6-5b99-ab81-27f5d28dcbe4
DOI: 10.21203/rs.3.rs-9578420/v1

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Deoxyshikonin Ameliorates High Glucose-Induced Dysfunction of Human Umbilical Vein Endothelial Cells and Promotes Wound Healing in Diabetic Mice by Regulating hsa-HLA- DRB1DOI 10.21203/rs.3.rs-9578420/v1Read

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