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Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data

4 Jul 2025

Abstract excerpt

BACKGROUND: Oxidative stress plays a crucial role in the development of diabetic foot ulcers (DFU). However, its underlying mechanisms are not fully understood. The purpose of this study was to use bioinformatics and preliminary validation methods to preliminarily reveal the oxidative stress landscape in DFU. METHODS: Based on the single-cell and bulk RNA sequencing data of DFU, we conducted differential genes...

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Share to Diabetic Foot Ulcer Assessment and Management
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40616164
DOI: 10.1186/s13062-025-00672-5

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