Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the microenvironment of diabetic foot ulcers and potential drug identification based on scRNA-seq

4 Jan 2023

Abstract excerpt

Background: Diabetes foot ulcers (DFUs) are a type of foot infection, ulcer, and/or deep tissue destruction caused by neuropathy and vascular disease in the distal extremities of diabetic patients. Its pathogenesis and its microenvironment are not entirely understood. Methods: Initially, the GSE165816 data set from the GEO database was utilized for single cell analysis to reveal the microenvironment and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetic Foot Ulcer Assessment and Management
Share to Mesenchymal stem cell research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36686438
DOI: 10.3389/fendo.2022.997880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the microenvironment of diabetic foot ulcers and potential drug identification based on scRNA-seqPMID 36686438Read ↗

Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing dataSemantic proximity Read ↗

Healing mechanism of diabetic foot ulcers using single-cell RNA-sequencingSemantic proximity Read ↗

Deciphering and verifying cuproptosis-associated hub genes in diabetic foot ulcer by combining single-cell and bulk RNA-sequencingSemantic proximity Read ↗

Single-cell RNA sequencing and transcriptomic analysis reveal the critical signatures involved in nonhealing diabetic foot ulcersSemantic proximity Read ↗

Single-cell RNA sequencing reveals the impaired epidermal differentiation and pathological microenvironment in diabetic foot ulcerSemantic proximity Read ↗

Identification of SASP-associated biomarkers and regulatory mechanisms in diabetic foot ulcers based on transcriptomics and experimental validationSemantic proximity Read ↗

Single-cell RNA sequencing reveals a new mechanism of endothelial cell heterogeneity and healing in diabetic foot ulcersSemantic proximity Read ↗

Role of M1 macrophages in diabetic foot ulcers and related immune regulatory mechanismsSemantic proximity Read ↗

Identifying and Validating Extracellular Matrix-Related Gene CTSH in Diabetic Foot Ulcer Using Bioinformatics and Machine LearningSemantic proximity Read ↗

Single Cell Transcriptomic Landscape of Diabetic Foot UlcersSemantic proximity Read ↗

Combined analysis of single-cell sequencing and bulk transcriptome sequencing reveals new mechanisms for non-healing diabetic foot ulcersSemantic proximity Read ↗

Integrated genetic analysis of diabetic complications: Bioinformatics insights into foot ulcers, neuropathy and peripheral artery diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.