Article

MRI-Derived Fat Depots and Cardiometabolic Pathways Underlying Heart Failure Risk: A Mendelian Randomization Study

2026-07-10

Abstract excerpt

<h4>Background</h4> Obesity is a major modifiable risk factor for heart failure (HF), but body mass index (BMI) does not distinguish biologically distinct fat depots. Whether imaging-derived adipose tissue depots capture specific cardiometabolic pathways underlying HF risk beyond conventional anthropometric measures remains uncertain. <h4>Methods</h4> We performed two-sample Mendelian randomization (MR) and mult...

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Literature Corpus work: 9a4b8db9-3f78-51b9-85ae-5ecee812f7eb
DOI: 10.64898/2026.07.06.26357230

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