Article

Apoptosis: Reprogramming and the Fate of Mature Cells

2012-04-17

Abstract excerpt

Apoptosis is essential for embryogenesis, organ metamorphosis, and tissue homeostasis. In embryonic stem cells, self-renewal is balanced with proliferative potential, inhibition of differentiation, and prevention of senescence and apoptosis. Growing evidence supports the role of apoptosis in self-renewal, differentiation of pluripotent stem cells, and dedifferentiation (reprogramming) of somatic cells. In this pap...

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Literature Corpus work: 9a20f647-fd65-5cf2-b026-e3d25af2ee9e
DOI: 10.5402/2012/685852

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