APOPTOSIS AND DISEASE: Regulation and Clinical Relevance of Programmed Cell Death

Abstract excerpt

Regulation of the homeostatic balance between cell proliferation and cell death is essential for development and maintenance of multicellular organisms. Physiologic, or programmed, cell death is dependent on a genetically encoded and evolutionarily conserved pathway that induces a form of cellular suicide known as apoptosis. In the past decade, it has become clear that the regulatory mechanisms controlling...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer-related Molecular Pathways
• Share to Cell death mechanisms and regulation
• Share to Ubiquitin and proteasome pathways