[Apoptosis in disease].

Abstract excerpt

BACKGROUND: Apoptosis, the death of a single cell according to an exactly defined intracellular program, is a key principle allowing embryonic development and later on tissue homeostasis in metazoans. MOLECULAR BASE: The molecular base is an evolutionary highly conserved intracellular signaling cascade, which is preserved from hematodes to mammals. Initiation of the program finally leads to the activation of...

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