Article
NHAPL analysis of glycoRNA reveals sialic acid-containing glycosylated mRNA 3′UTRs and enables sensitive SLE diagnostics
2026-02-09
Abstract excerpt
GlycoRNA, newly identified RNA molecules bearing glycan modifications on cell membranes, is implicated in cell communication and immune regulation. However, current technological limitations impede a thorough elucidation of their biological roles and clinical significance. Here, we developed N ucleotides H ybridization and A ptamer-based P roximity L igation (NHAPL), a homogeneous assay enabling sensitive and...
Topics
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- Advanced biosensing and bioanalysis techniques
- Advanced Biosensing Techniques and Applications
- Galectins and Cancer Biology
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- RNA regulation and disease
- Systemic Lupus Erythematosus Research
- Viral Infections and Immunology Research
Identifiers and source
- Literature Corpus work
- 99db1612-d1e7-5ffa-9cd8-d31c7e2a8ce3
- DOI
- 10.64898/2026.02.05.26345357