Article

HPV 16 E7 Alters Translesion Synthesis Signaling

2022-07-06

Abstract excerpt

A subset of human papillomaviruses (HPVs) are the cause of virtually every cervical cancer. These so called “high risk” HPVs two major oncogenes (HPV E6 and E7) that are necessary for transformation. Among "high risk” HPVs, HPV16 causes most cervical cancers and is often used as a representative model for oncogenic HPVs. HPV16 E7 facilitates the vial lifecycle by the binding and destabilizing RB, which ensures the...

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Literature Corpus work: 99d887fd-2bbd-5e02-ae7c-4a062a64f412
DOI: 10.21203/rs.3.rs-1795099/v1

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