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Systemic CD8+ T cell effector signature predicts prognosis of lung cancer immunotherapy

2024-09-18

Abstract excerpt

<h4>Background</h4> While immune checkpoint inhibitors (ICIs) are adopted as standard therapy in non-small cell lung cancer (NSCLC) patients, factors that influence variable prognosis still remain elusive. Therefore, a deeper understanding is needed of how germline variants regulate the transcriptomes of circulating immune cells in metastasis, and ultimately influence immunotherapy outcomes. <h4>Methods</h4> We...

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Literature Corpus work
99903ad8-aba4-5858-a4c8-aac5d1fc66cb
DOI
10.1101/2024.09.16.613381
Open publication

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Systemic CD8+ T cell effector signature predicts prognosis of lung cancer immunotherapyDOI 10.1101/2024.09.16.613381
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