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CD8+ T Cell-Associated Gene Signature Correlates With Prognosis Risk and Immunotherapy Response in Patients With Lung Adenocarcinoma

22 Feb 2022

Abstract excerpt

The presence of infiltrating CD8 + T lymphocytes in the tumor microenvironment of lung adenocarcinoma (LUAD) is correlated with improved patient prognosis, but underlying regulatory mechanisms remain unknown. To identify biomarkers to improve early diagnosis and treatment of LUAD, we downloaded 13 immune cell line-associated datasets from the GEO database. We identified CD8 + T cell-associated genes via weighted...

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PMID: 35273597
DOI: 10.3389/fimmu.2022.806877

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