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A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics

2024-10-22

Abstract excerpt

The human gut microbiome is intrinsically involved in health and disease, representing a wealth of untapped therapeutic potential. Here, we demonstrate the utility and potential of a metagenome guided, large cohort-based approach for the rational selection of live biotherapeutics from the human gut. We applied this approach to Inflammatory Bowel Disease (IBD), identifying several lead candidates that were signific...

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Identifiers and source

Literature Corpus work
87a2d492-f154-579b-94d7-0c1f7f800bc8
DOI
10.1101/2024.10.22.619608
Open publication

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A rational approach for the targeted discovery and characterisation of microbiome-derived therapeuticsDOI 10.1101/2024.10.22.619608
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