Article

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

2021-06-10

Abstract excerpt

<h4>Background</h4> Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation in human and mouse. A systematic analysis of how this variation impacts epigenetic states and expression of the rDNA has thus far not been performed. <h4>Results</h4> Using a combination of long- and short-read sequencing, we establish that 45S rDNA units in the C57BL/6J mouse strain exist as distinct genetic haploty...

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Literature Corpus work: 99706dda-f454-5257-af53-104a505025cd
DOI: 10.1101/2021.06.10.447887

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