Article
The role of endogenous retrotransposable elements in Parkinson's disease
2021-01-01
Abstract excerpt
Parkinson's disease (PD) is a progressive neurodegenerative disorder resulting in significant damage to dopaminergic neurons within the basal ganglia of the brain leading to a deficiency of dopamine. PD is classed as a polygenic disease with multiple known mutations which infer risk of development and impact the age of disease onset. The latest genome-wide association studies (GWAS) indicate approximately 90 indep...
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Identifiers and source
- Literature Corpus work
- 991e5e74-13f8-5874-9e0f-b85173a246d8
- DOI
- 10.17638/03126606
