Article
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson's disease.
Experimental biology and medicine (Maywood, N.J.) - 1 Sept 2022
Kõks Sulev, Pfaff Abigail L, Singleton Lewis M, Bubb Vivien J, Quinn John P
Abstract excerpt
The pathophysiology of Parkinson's disease (PD) is a complex process of the interaction between genetic and environmental factors. Studies on the genetic component of PD have predominantly focused on single nucleotide polymorphisms (SNPs) using a cross-sectional case-control design in large genome-wide association studies. This approach while giving insight into a significant portion of the genetics of PD does...
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