Article

KmerSignificance Score: A discriminative and biologically-informed framework for viral <i>k</i> -mer prioritization

2026-05-21

Abstract excerpt

Distinguishing closely related viral strains requires identifying genomic regions where subtle sequence differences carry biological significance. While k -mer-based approaches offer computational efficiency for genome analysis, existing methods lack standardized frameworks for evaluating which k -mers are most informative. Current selection strategies focus primarily on statistical discriminative power without...

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Literature Corpus work: 990ba4a0-eb39-55d1-bc87-ad3d015635c3
DOI: 10.64898/2026.05.15.725339

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