Article

BlueNuclei: automated identification and classification of live and dead transfected neurons using interpretable features

2026-02-02

Abstract excerpt

In vitro modeling of neuronal disorders using transfected primary neurons is one of the fundamental approaches for studying disease mechanisms and therapeutic screening. Assessing neuronal viability is an everyday yet critical task in such experiments and requires accurate identification and classification of live and dead transfected neurons from dual-channel fluorescence images; however, this step is typically p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9909a223-b126-5359-b485-a226c2b277be
DOI: 10.64898/2026.01.29.702657

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

BlueNuclei: automated identification and classification of live and dead transfected neurons using interpretable featuresDOI 10.64898/2026.01.29.702657Read

Image-based deep learning reveals the responses of human motor neurons to stress and ALSSemantic proximity Read

Deep Disentangled Representation Learning Reveals Neuron Subtype-Specific Nuclear Morphologies Across Aging in Mice and HumansSemantic proximity Read

Deep learning in human neurons predicts mechanistic subtypes of Parkinson’sSemantic proximity Read

Machine learning–based image analysis of Parkinson’s disease iPS cell-derived neurons predicts genotype and reveals mitochondria–lysosome abnormalitiesSemantic proximity Read

Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.Semantic proximity Read

Image-based phenotyping of disaggregated cells using deep learning.Semantic proximity Read

Organellomics: AI-driven deep organellar phenotyping reveals novel ALS mechanisms in human neuronsSemantic proximity Read

Predictive Cellular Signatures from Live Human Motor Neurons Distinguish TDP-43 ALS and Enable ALS Subtype StratificationSemantic proximity Read

Image-based Cell Phenotyping Using Deep LearningSemantic proximity Read

Super-human cell death detection with biomarker-optimized neural networksSemantic proximity Read

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localizationSemantic proximity Read

Label-free classification of cell death pathways via holotomography-based deep learning frameworkSemantic proximity Read