Article

Prime Editing in vivo: Correcting the Leptin Receptor of db/db Mice

2024-05-07

Abstract excerpt

Genetic diseases can be caused by monogenic diseases, which result from a single gene mutation in the DNA sequence. Many innovative approaches have been developed to cure monogenic genetic diseases, namely by genome editing. A specific type of genomic editing, prime editing, has the potential advantage to edit the human genome without requiring double-strand breaks or donor DNA templates for editing. Additionally,...

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Literature Corpus work: 98b2e793-d06a-546c-aa6b-b942852e817f
DOI: 10.22541/au.171507305.55377808/v1

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