Article

Mice lacking <i>Ptprd</i> exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating

2022-10-28

Abstract excerpt

Protein Tyrosine Phosphatase receptor type D (PTPRD) is a member of the protein tyrosine phosphatase family that mediates cell adhesion and synaptic specification. Genetic studies have linked Ptprd to several neuropsychiatric phenotypes, including Restless Leg Syndrome (RLS), opioid abuse disorder, and antipsychotic-induced weight gain. Genome-wide association studies (GWAS) of either pediatric obsessive-compulsi...

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Literature Corpus work: 988b2d8d-b615-5e4b-b98b-184861cf19b9
DOI: 10.1101/2022.10.28.514214

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