Article

Questioned validity of Gene Expression Dysregulated Domains in Down's Syndrome

2015-07-17

Abstract excerpt

Recently, in studies examining fibroblasts obtained from the tissues of one set of monozygotic twins (i.e. fetuses derived from the same egg) discordant for trisomy 21 (Down syndrome; DS), Letourneau et al., reported the presence of a defined pattern of dysregulation within specific genomic domains they referred to as G ene E xpression D ysregulated D omains (GEDDs). GEDDs were described as alternating segm...

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Literature Corpus work: 987f0d05-9d44-5ab1-9a84-957797f5d241
DOI: 10.12688/f1000research.6735.1

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