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Article

Gene expression profiling of amniotic fluid mesenchymal stem cells of monozygotic twins discordant for trisomy 21.

Gene - 15 May 2020

You Shu-Han, Lee Yun-Shien, Chang Yu-Jen, Lin Chiao-Yun, Wang Tzu-Hao, Chang Yao-Lung

Abstract excerpt

Down syndrome is one of the most common chromosomal disorders and yet our understanding about the dysregulated genes in this disease is limited. Through this case study, we investigated the gene expression profile of primary amniotic fluid mesenchymal stem cells (AFMSCs) isolated from the amniotic sac of monozygotic twins discordant for trisomy 21 with one fetal hydrops at 17 weeks of gestation. AFMSCs were...

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Identifiers

PMID: 32057927
DOI: 10.1016/j.gene.2020.144461

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