Article

Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood Transcriptomics

2024-11-19

Abstract excerpt

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by challenges in social communication, repetitive behaviors, and restricted interests. Recent research has emphasized the importance of metabolic dysfunctions in the pathophysiology of ASD. This study investigates metabolic alterations associated with ASD by analyzing transcriptomic data obtained from the prefrontal cortex (bulk tissue...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 98703536-dfb2-503b-82b6-4746e822c46e
DOI: 10.1101/2024.11.18.624092

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood TranscriptomicsDOI 10.1101/2024.11.18.624092Read

Metabolomics analysis of children with autism, idiopathic-developmental delays, and Down syndromeSemantic proximity Read

Phenotypically driven subgroups of ASD display distinct metabolomic profiles.Semantic proximity Read

A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeutic TranslationSemantic proximity Read

A metabolomics approach to parsing the heterogeneity of autism identifies complex dysregulations of cellular bioenergeticsSemantic proximity Read

Metabolomic biomarkers in autism: identification of complex dysregulations of cellular bioenergeticsSemantic proximity Read

Biochemical, Genetic and Clinical Diagnostic Approaches to Autism-Associated Inherited Metabolic DisordersSemantic proximity Read

Neurometabolic disorders and dysfunction in autism spectrum disorders.Semantic proximity Read

Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder.Semantic proximity Read

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2-deficient murine astrocytesSemantic proximity Read

Investigation of cell metabolism dysfunction in autism spectrum disorders using genome-scale metabolic network analysis of neuronal developmentSemantic proximity Read

Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA ProfilingSemantic proximity Read

A study of genetic heterogeneity in autism spectrum disorders based on plasma proteomic and metabolomic analysis: multiomics study of autism heterogeneitySemantic proximity Read