Article

Investigation of cell metabolism dysfunction in autism spectrum disorders using genome-scale metabolic network analysis of neuronal development

2024-10-03

Abstract excerpt

Autism Spectrum Disorders (ASDs) are a group of highly heterogeneous neurodevelopmental conditions characterized by impairments in social interactions and repetitive behaviors. In spite of extensive efforts, known genetic mutations can hardly explain the ASD cases, which signifies the highly heterogeneous nature of ASDs and calls for shifting to a more holistic approach for understanding the mechanism of these dis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bb0f88ba-1518-5b35-9d7d-400de94b7b2f
DOI: 10.1101/2024.10.01.616152

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigation of cell metabolism dysfunction in autism spectrum disorders using genome-scale metabolic network analysis of neuronal developmentDOI 10.1101/2024.10.01.616152Read

Biochemical, Genetic and Clinical Diagnostic Approaches to Autism-Associated Inherited Metabolic DisordersSemantic proximity Read

Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood TranscriptomicsSemantic proximity Read

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2-deficient murine astrocytesSemantic proximity Read

De novo mutations within metabolism networks of amino acid/protein/energy in Chinese autistic children with intellectual disability.Semantic proximity Read

Phenotypically driven subgroups of ASD display distinct metabolomic profiles.Semantic proximity Read

Metabolomics of autism spectrum disorders: early insights regarding mammalian-microbial cometabolites.Semantic proximity Read

The metabolic role of vitamin D in children’s neurodevelopment: a network studySemantic proximity Read

Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes.Semantic proximity Read

Metabolomics: Perspectives on Clinical Employment in Autism Spectrum Disorder.Semantic proximity Read

Connecting the dots: Overlaps between autism and cancer suggest possible common mechanisms regarding signaling pathways related to metabolic alterations.Semantic proximity Read

A study of genetic heterogeneity in autism spectrum disorders based on plasma proteomic and metabolomic analysis: multiomics study of autism heterogeneitySemantic proximity Read

Metabolic pathways and genes involved in treatable and non-treatable metabolic epilepsies. A comprehensive review and metabolic pathway analysisSemantic proximity Read