Article

Marine derivative CHNQD-00603 reverses bone marrow mesenchymal stem cells senescence by enhancing autophagy through the AKT/ERK/mTOR signaling pathway

2024-04-11

Abstract excerpt

<h4>Objective: </h4> Maxillofacial bone defect caused by the tumor and periodontal disease in the elderly will affect implant restoration. Bone marrow mesenchymal stem cells (BMSCs), as seed cells for bone regeneration, play an important role in the treatment of bone defects. The objective of this study was to investigate the effect and mechanism of marine derivative CHNQD-00603 on senescence BMSCs. Materials and...

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Literature Corpus work: 985059be-9b24-5511-8e87-bb6044388540
DOI: 10.21203/rs.3.rs-4229655/v1

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