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Article

Inducible, but not constitutive, pancreatic <i>REG/Reg</i> isoforms are regulated by intestinal microbiota and pancreatic diseases

2024-10-22

Abstract excerpt

The REG / Reg gene locus encodes for a conserved family of potent antimicrobial but also pancreatitis-associated proteins. Here we investigated whether REG/Reg family members differ in their baseline expression levels and abilities to be regulated in the pancreas and gut upon perturbations. We found, in human and mouse, pancreas and gut differed in REG / Reg isoform levels and preferences, with duodenum most...

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Identifiers and source

Literature Corpus work
9845d4f3-a0c7-5292-be7e-9636b10f7322
DOI
10.1101/2024.10.18.619139
Open publication

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Inducible, but not constitutive, pancreatic <i>REG/Reg</i> isoforms are regulated by intestinal microbiota and pancreatic diseasesDOI 10.1101/2024.10.18.619139
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