Article

Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

2020-03-08

Abstract excerpt

Obstructive sleep apnea (OSA) results from episodes of airway collapse and intermittent hypoxia and is associated with a host of health complications including dementia, diabetes, heart failure, and stroke. Although the lung is the first organ to sense changes in inspired oxygen levels, little is known about the consequences of IH to the lung hypoxia-inducible factor (HIF)-responsive pathways. Furthermore, cellula...

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Literature Corpus work: 983b4fbb-7089-5f8a-b64c-a7fe1aeed1a6
DOI: 10.1101/2020.03.06.981241

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