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Article

Hypoxia Selectively Activates the CREB Family of Transcription Factors in the In Vivo Lung

8 Aug 2008

Abstract excerpt

RATIONALE: Pulmonary hypertension is a common complication of chronic hypoxic lung diseases and is associated with increased morbidity and reduced survival. The pulmonary vascular changes in response to hypoxia, both structural and functional, are unique to this circulation. OBJECTIVES: To identify transcription factor pathways uniquely activated in the lung in response to hypoxia. METHODS: After exposure to...

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PMID: 18689465
DOI: 10.1164/rccm.200712-1890oc

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