Article

Interplay Between Human Leukocyte Antigen Genes and the Microbial Colonization Process of the Newborn Intestine

2009-05-28

Abstract excerpt

Coeliac disease (CD) development involves genetic (HLA-DQ2/DQ8) and environmental factors. Herein, the influence of the HLA-DQ genotype on the gut colonization process of breast-fed children was determined. A cohort of 20 newborns, with at least one first-degree relative with CD, were classified according to their HLA-DQ genotype into high, intermediate and low genetic risk groups, showing 24-28%, 7-8% and less th...

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Literature Corpus work: 983ae030-942c-5e9c-8ddf-94fd7ef0154c
DOI: 10.21775/cimb.012.001

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