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Article

Interplay between human leukocyte antigen genes and the microbial colonization process of the newborn intestine.

Current issues in molecular biology - 1 Jan 2010

De Palma G, Capilla A, Nadal I, Nova E, Pozo T, Varea V, Polanco I, Castillejo G, López A, Garrote J A, Calvo C, García-Novo M D, Cilleruelo M L, Ribes-Koninckx C, Palau F, Sanz Y

Abstract excerpt

Coeliac disease (CD) development involves genetic (HLA-DQ2/DQ8) and environmental factors. Herein, the influence of the HLA-DQ genotype on the gut colonization process of breast-fed children was determined. A cohort of 20 newborns, with at least one first-degree relative with CD, were classified according to their HLA-DQ genotype into high, intermediate and low genetic risk groups, showing 24-28%, 7-8% and less...

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PMID: 19478349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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