Article
Gut bacterial and fungal signatures in relation to human leukocyte antigen-DQ2/DQ8 in children with celiac disease and siblings.
World journal of gastroenterology - 14 Mar 2026
Salamon Dominika, Krawczyk Agnieszka, Zapała Barbara, Duplaga Mariusz, Kowalska-Duplaga Kinga, Gosiewski Tomasz
Abstract excerpt
BACKGROUND: The presence of human leukocyte antigen (HLA)-DQ2 and/or HLA-DQ8 alleles is necessary but not sufficient for the development of celiac disease (CeD). This suggests that additional environmental and biological factors, including bacteria and, above all, the still rarely studied fungal gut microbiota, play key roles in disease onset and progression. AIM: To characterize and compare the intestinal...
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