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Article

TTI-0102: A Novel Natural Controlled-Release Cysteamine Prodrug for Mitochondrial Disease and Cystinosis

2026-03-31

Abstract excerpt

<h4>Background</h4> Cysteamine is the only disease-modifying therapy for nephropathic cystinosis and has shown promise in mitochondrial disorders, but its clinical utility is limited by poor tolerability due to high peak concentrations with existing formulations. TTI-0102 is a novel natural controlled-release cysteamine prodrug designed to provide sustained cysteamine exposure with improved tolerability. <h4>Meth...

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Literature Corpus work
98119deb-c76b-5a87-a1f4-155242e886b4
DOI
10.64898/2026.03.26.26347968
Open publication

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