Article

Impact of sodium butyrate and mild hypothermia on metabolic and physiological behaviour of CHO TF 70R cells

2017-05-01

Abstract excerpt

To reduce costs associated with productivity of recombinant proteins in the biopharmaceutical industry, research has been focused on regulatory principals of growth and survival during the production phases of the cell culture. The main strategies involve the regulation of cell proliferation by the modulation of cell cycle control points (G1/S or G2/M) with mild hypothermia and the addition of sodium butyrate (NaB...

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Literature Corpus work: 97962a9e-7ac1-5e6e-b299-bd02c0c0f628
DOI: 10.1016/j.ejbt.2017.03.008

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