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<i>LRRK2</i> in Focus: A Global Browser Linking Genetic Diversity to Functional Effects

2026-07-04

Abstract excerpt

<h4>Background</h4> LRRK2 variants are major contributors to Parkinson’s disease (PD). Many pathogenic variants increase kinase activity, underscoring the value of functional assays in nominating therapeutic targets and kinase inhibitors as potential disease-modifying therapies. <h4>Objective</h4> To develop an interactive resource that provides functional context and ancestry-specific variant frequencies. <h4>...

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Literature Corpus work
97922b96-c2b6-51fb-80da-bb49abe522e8
DOI
10.64898/2026.07.01.26357034
Open publication

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<i>LRRK2</i> in Focus: A Global Browser Linking Genetic Diversity to Functional EffectsDOI 10.64898/2026.07.01.26357034
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