Article

Age and sex alter the immune response in a chronic fibrosis model via changes in T cell and macrophage phenotype

2026-08-28

Abstract excerpt

The foreign body response (FBR) is an immune mediated event that occurs with every material implant. The extent of the fibrosis is dependent on many factors including the biomaterial design, tissue location, and host factors such as age, sex, ancestry, diet. There are known clinical outcomes of implants dependent on age and sex, including increased fibrosis and implant failure in aged and female patients. As the p...

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Literature Corpus work: 977b4d73-bcc5-552c-83a8-8c60b83f457d
DOI: 10.64898/2026.08.27.747581

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