Article

Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons

2023-03-07

Abstract excerpt

The expression of linear DNA sequences is precisely regulated by the three–dimensional (3D) architecture of chromatin. Morphine-induced aberrant gene networks of neurons have been extensively investigated; however, how morphine impacts the 3D genomic architecture of neuorns is still unknown. Here, we applied digestion-ligation-only high-throughput chromosome conformation capture (DLO Hi-C) technology to investigat...

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Literature Corpus work: 97756d9c-aae5-52fb-beb0-91aeb70772cf
DOI: 10.1101/2023.03.06.531278

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