Article

NUDT21 Regulates Macrophage Cytokine Responses via Alternative Polyadenylation in ARDS

2025-10-24

Abstract excerpt

<title>Abstract</title> <p> Acute respiratory distress syndrome (ARDS) is a life-threatening condition driven by uncontrolled inflammation and immune dysregulation. The post-transcriptional mechanisms that fine-tune macrophage activation in ARDS remain poorly understood. Here, we identify Nudix hydrolase 21 (NUDT21) as a critical regulator of macrophage-mediated inflammation through alternative polyadenylation (...

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Literature Corpus work: 97690ca6-0194-5106-b7e7-a90b9eb3b97a
DOI: 10.21203/rs.3.rs-7810883/v1

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