Back to search

Article

Tight Spaces, Big Discoveries: Decoding Human Adhesion Biology with Avian Chorioallantoic Membrane Xenograft Models

2026-01-13

Abstract excerpt

Tight junction (TJ) proteins such as Junctional Adhesion Molecule-A (JAM-A), claudins, and occludin play increasingly recognised roles in cancer biology beyond their structural functions, influencing tumour proliferation, invasion, metastasis and therapy resistance. Understanding how these proteins modulate tumour progression in vivo requires models that are both physiologically relevant and ethically viable. The...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9731c0e0-a1b8-5c20-897a-300c007b5b86
DOI
10.20944/preprints202601.0923.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Tight Spaces, Big Discoveries: Decoding Human Adhesion Biology with Avian Chorioallantoic Membrane Xenograft ModelsDOI 10.20944/preprints202601.0923.v1
In ovo model in cancer research and tumor immunologySemantic proximity
Engineered endothelial cell grafts form functional anastomoses and enable recruitment of intravenously delivered human T cells in CAM tumor modelsSemantic proximity
Technical Implications of the Chicken Embryo Chorioallantoic Membrane Assay to Elucidate Neuroblastoma BiologySemantic proximity
Xenografting Human Musculoskeletal Sarcomas in Mice, Chick Embryo, and Zebrafish: How to Boost Translational ResearchSemantic proximity
The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Target and Compound EvaluationSemantic proximity
Non-Animal Technologies to Study and Target the Tumour Vasculature and AngiogenesisSemantic proximity
The experimental renal cell carcinoma model in the chick embryo.Semantic proximity
Characteristics of in Vivo Model Systems for Ovarian Cancer StudiesSemantic proximity
Optimization of the chicken chorioallantoic membrane assay as reliable in vivo model for the analysis of osteosarcomaSemantic proximity
Modeling pancreatic cancer tumor stroma co-evolution in an <i>in ovo</i> modelSemantic proximity
Embryonated Chicken Tumor Xenografts Derived from Circulating Tumor Cells as a Relevant Model to Study Metastatic Dissemination: A Proof of ConceptSemantic proximity
Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis.Semantic proximity
Select a neighboring publication to make it the new centre.