Article
The experimental renal cell carcinoma model in the chick embryo.
Angiogenesis - 1 Jan 2013
Fergelot Patricia, Bernhard Jean-Christophe, Soulet Fabienne, Kilarski Witold W, Léon Céline, Courtois Nathalie, Deminière Colette, Herbert John M J, Antczak Philipp, Falciani Francesco, Rioux-Leclercq Nathalie, Patard Jean-Jacques, Ferrière Jean-Marie, Ravaud Alain, Hagedorn Martin, Bikfalvi Andreas
Abstract excerpt
The clear cell subtype of renal carcinoma (CCRCC) is highly vascularized and despite a slow progression rate, it is potentially a highly aggressive tumor. Although a doubling of median progression-free survival in CCRCC patients treated by targeted therapies has been observed, the fact that tumors escape after anti-VEGF treatment suggests alternative pathways. The chick chorioallantoic membrane (CAM) is a...
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