Article

Identification of volatile metabolites produced from gut microbial levodopa metabolism using an untargeted metabolomics approach

2023-09-19

Abstract excerpt

<title>Abstract</title><p>Interspecies pathways in the gut microbiome have been shown to metabolize levodopa, the primary treatment for Parkinson’s disease, and reduce its bioavailability. While the enzymatic reactions have been identified, the ability to establish the resulting macromolecules as biomarkers of microbial metabolism remains technically challenging. In this study, we leveraged an untargeted mass spec...

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Literature Corpus work: 97237ad3-0e7a-55b6-8e92-2a30a764a43f
DOI: 10.21203/rs.3.rs-3335592/v1

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